Is the "X" a multiplication sign?
If the two ?s are meant to represent the same variable, then finding the one unique solution is fairly straightforward \(\displaystyle \left(\dfrac{5}{4} \cdot x = 25 \implies x = \text{??}\right)\). On the other hand, if they're meant to be two different variables, then there is no unique solution. The best you could do it to solve one variable in terms of the other.
OK...so the X is * and the ?'s are same...
Try and be CLEARER next time:
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So ? + (1/4 X ?) = 25 is really:
a + (1/4)*a = 25 ; multiply by 4:
4a + a = 100
5a = 100
Only 1 solution. What is it?