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This polynomial is quadratic, in form. So, we could make a temporary substitution and then use the Quadratic Formula to find the roots.
For example: let z = x^2
Then we have z^2 - 5z + 4. Find the roots for this polynomial, and then set them equal to x^2 and solve for x.
Another approach is using the Rational Roots Theorem. That provides six possiblities, and it's a simple matter to check them.
Once we have the roots, the factorization is trivial.
What methods have you studied, so far? I mean, if you make some statements about what you already know or tried, I could provide specific help.