The way you wrote the question without any parenthesis, here's what I read:
\(\displaystyle \L y = \sqrt{5x} - \sqrt{\frac{5}{x}}
= \sqrt{5} \; x^{1/2} - \sqrt{5} \; x^{-1/2}
= \sqrt{5} \left( x^{1/2} - x^{-1/2} \right)\)
Now take the derivative using power rule,
\(\displaystyle \L \frac{dy}{dx} = \sqrt{5} \left( \frac{1}{2} x^{-1/2} + \frac{1}{2} x^{-3/2} \right) = \frac{\sqrt{5}}{2} \left( \frac{1}{\sqrt{x}} + \frac{1}{x\sqrt{x}} \right)\)
and simplify... If the question is different, convert radicals to powers and repeat the method.