What part do you need help with ? Have you learned this property ?
x^(-3) * x^(1/2)
x^(-3 + 1/2)
x^(-5/2)
When powers of the same base are multiplied together, we just add the exponents.
Now you do the same thing, in the denominator.
x^(3/2) * x^(-1)
After you simplify the line above, you have a new ratio. Finish, by using another property for a ratio of like powers.
When powers of the same base are in ratio, we subtract the bottom exponent from the top exponent, ike this:
x^(-5/2) over x^(1/2)
x^(- 5/2 - 1/2)
x^(-3)
Can you ask specific questions ?